中国麻风皮肤病杂志 ›› 2020, Vol. 36 ›› Issue (3): 158-160.doi: 10.12144/zgmfskin202003158

• 短篇论著 • 上一篇    下一篇

52例原发性皮肤淀粉样变病因分析

宋婷1,闵仲生1,李红敏1,蔡滨2,时悦1,谭城1   

  1. 1江苏省中医院皮肤科，江苏南京，210029；2东南大学附属中大医院，江苏南京，210009
  • 出版日期:2020-03-15 发布日期:2020-03-30
  • 通讯作者: 谭城，E-mail：tancheng@yeah.net

Analysis of risk factors of the 52 patients with primary cutaneous amyloidosis

SONG Ting1, MIN Zhongsheng1, LI Hongmin1, CAI Bin2, SHI Yue1, TAN Cheng1   

  1. 1 Jiangsu Province Hospital of Chinese Medicine, Nanjing 210029, China; 2 Zhongda Hospital Affiliated to Southeast University, Nanjing 210009, China
  • Online:2020-03-15 Published:2020-03-30
  • Contact: TAN Cheng, E-mail: tancheng@yeah.net

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摘要： 目的：明确原发性皮肤淀粉样变患者发病相关因素。方法：对2018年3月至2019年1月我院52例原发性皮肤淀粉样（PCA）变患者及104名正常对照的资料进行分析。结果：多因素 Logistic回归分析显示原发性皮肤淀粉样变的发病因素中日光暴晒、搔抓、过敏为危险因素，OR值分别为3.044，9.254，4.653，P均<0.05。合并疾病中，湿疹、荨麻疹、过敏性鼻炎发病率在PCA患者与104名健康正常对照间比较，差异有统计学意义（P<0.05）。结论：日光暴晒、搔抓、过敏与原发性皮肤淀粉样变的发病有关，患者易合并湿疹、荨麻疹、过敏性鼻炎。

Abstract: Objective: To determine the influence factors of primary cutaneous amyloidosis (PCA). Methods: The data of 52 patients with primary cutaneous amyloidosis (PCA) in our hospital from May 2018 to January 2019 was analyzed. Results: A multivariable unconditional logistic regression showed that the excess sunlight, scratching and allergy were associated risk factors (OR=3.04, 9.25 and 4.65，respectively (Ps<0.05). There were significant differences in morbidity of eczema, urticaria and allergic rhinitis between 52 PCA patients and 104 healthy controls (P＜0.05). Conclusion: The sunlight, scratching and allergy are associated with PCA and the complicating diseases include eczema, urticaria and allergic rhinitis.