中国麻风皮肤病杂志 ›› 2021, Vol. 37 ›› Issue (9): 568-570.doi: 10.12144/zgmfskin202109568

• 论著 • 上一篇    下一篇

寻常型天疱疮合并急性肺栓塞危险因素分析

王玥1,严煜林2   

  1. 1广西医科大学附属武鸣医院，南宁，530199；2广西医科大学第一附属医院，南宁，530022
  • 出版日期:2021-09-15 发布日期:2021-08-04
  • 通讯作者: 严煜林，E-mail: yanyulin0771@163.com

Analysis of risk factors for pemghigus vulgaris combined with acute pulmonary embolism

WANG Yue1, YAN Yulin2   

  1. 1 Wuming Hospital of Guangxi Medical University, Nanning 530199, China; 2 The First Affiliated Hospital of Guangxi Medical University, Nanning 530022, China
  • Online:2021-09-15 Published:2021-08-04
  • Contact: YAN Yulin, E-mail: yanyulin0771@163.com

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摘要： 目的：分析寻常型天疱疮合并急性肺栓塞（acute pulmonary embolism，APE）的危险因素。方法：回顾性分析2012年至2020年7例寻常型天疱疮合并急性肺栓塞患者（观察组），50例寻常型天疱疮未合并急性肺栓塞患者（对照组）的临床资料。结果：7例患者突发APE时间在治疗寻常型天疱疮的第3～16天。观察组患者平均年龄为(57.28±14.24)岁，高于对照组（47.36±10.49）岁（P＝0.029）。与对照组比较，观察组卧床、肺部感染、高血压、高脂血症发病率高，病程短、血清白蛋白平均值低，差异均具有统计学意义（均P＜0.05）。 7例急性肺栓塞患者经积极诊治，最终痊愈 5例，好转2例。结论：寻常型天疱疮患者合并急性肺栓塞，可能与年龄、病程、卧床、肺部感染、低白蛋白、高血压及高血脂有关。

关键词: 寻常型天疱疮, 急性肺栓塞, 临床分析

Abstract: Objective: To analyze the risk factors of pemphigus vulgaris with acute pulmonary embolism (APE). Methods: The data of 7 patients with pemphigus vulgaris combined with APE from 2012 to 2020 were analyzed (observe group). And 50 pemphigus vulgaris patients without acute pulmonary embolism included as controls. Results: 7 patients had APE from day 3 to day 16 after treated for pemphigus vulgaris. The average age of onset of the patients in the observe group was (57.28±14.24) years old, which was higher than in the control group (47.36±10.49 years) (P＝0.029). Compared with the control group, the incidence rate of bedridden, lung infection, hypertensive and hyperlipidemia were higher in the observe group, with significant differences (Ps<0.05), and the value of serum albumin was lower and the course was shorter, with significant differences (Ps<0.05). Of 7 cases with APE, 5 were cured and 2 improved after treatment for  APE. Conclusion: The incidence of pemphigus vulgaris with acute pulmonary embolism may be related to age, course of disease, stay in bed, pulmonary infection, low albumin, hypertension and hyperlipidemia.

Key words: pemphigus vulgaris, pulmonary embolism, clinical analysis