中国麻风皮肤病杂志 ›› 2023, Vol. 39 ›› Issue (4): 272-274.doi: 10.12144/zgmfskin202304272

• 病例报告 • 上一篇    下一篇

NF1型恶性外周神经鞘瘤一例

祖丽胡玛尔·莫沙,布瓦杰尔·亚克亚,刘建勇,康晓静   

  1. 新疆维吾尔自治区人民医院皮肤性病科，新疆皮肤病临床医学研究中心，新疆皮肤病研究重点实验室（XJYS1707），乌鲁木齐，830001
  • 出版日期:2023-04-15 发布日期:2023-03-28

Malignant peripheral nerve sheath tumors with neurofibromatosis type 1: a case report

Zulihumaer·Mosha, Buwajieer·Yakeya, LIU Jianyong, KANG Xiaojing   

  1. Department of Dermatology and Venereology, People's Hospital of Xinjiang Uygur Autonomous Region, Xinjjiang Clinical Research Center For Dermatologic Diseases, Xinjiang Key Laboratory of Dermatology Research (XJYS1707), Urumqi 830001, China
  • Online:2023-04-15 Published:2023-03-28

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摘要： 患者，男，72岁。左下肢肿物10余年，加重1年。局部术后免疫组化：CD34阴性，CD31阴性，CD117阴性，NF阴性，Desmin阴性，SMA阴性，P53阴性，CK-Pan阴性，Ki-67大于40%，S-100阳性。结合家族史及临床表现，符合NF1型恶性外周神经鞘瘤诊断。

关键词: 恶性外周神经鞘瘤, 1型神经纤维瘤病

Abstract: A 72-year-old male presented with tumor on the left lower limb for more than 10 years and aggravated for 1 year. Immunohistochemical examination after local surgery showed CD34(-), CD31(-), CD117(-), NF(-), Desmin(-), SMA(-), P53(-), CK-Pan(-), Ki-67, more than 40%), S-100(+). Combined with family hitory and clinical manifestation, the diagnosis of malignant peripheral nerve sheath tumors with neurofibromatosis type 1 was macle.

Key words: malignant peripheral nerve sheath tumors, neurofibromatosis type 1