中国麻风皮肤病杂志 ›› 2025, Vol. 41 ›› Issue (1): 60-63.doi: 10.12144/zgmfskin202501060

• 病例报告 • 上一篇    下一篇

伴嗜酸性粒细胞增多性血管淋巴样增生一例并文献复习

袁现政1，魏世娟2，高菲2，邓晓彤3，司晓青2，高敏虹2   

  1. 1 济宁医学院临床医学院，山东济宁，272067；2 山东第一医科大学第一附属医院皮肤科，山东济南，250013；3 山东第一医科大学临床医学院，山东济南，250000
  • 出版日期:2025-01-15 发布日期:2024-12-23

Angiolymphoid hyperplasia with eosinophilia: a case report and literature review

YUAN Xianzheng1, WEI Shijuan2, GAO Fei2, DENG Xiaotong3, SI Xiaoqing2, GAO Minhong2   

  1. 1 Jining Medical University, Jining 272067, China; 2 Department of Dermatology, The First Affiliated Hospital of Shandong First Medical University, Jinan 250013, China; 3 School of Clinical Medicine, Shandong First Medical University, Jinan 250000, China
  • Online:2025-01-15 Published:2024-12-23

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摘要： 伴嗜酸性粒细胞增多性血管淋巴样增生是一种少见的良性肿瘤，临床上易误诊。本文报告1例，患者，女，55岁，左侧枕部头皮赘生物偶伴瘙痒半年余。皮损组织病理检查：表皮角化过度伴角化不全；真皮血管内皮细胞增生，细胞核凸向管腔，呈“墓碑状”；管周淋巴细胞等炎细胞浸润，未发现嗜酸性粒细胞。予以手术切除。

关键词: 伴嗜酸性粒细胞增多性血管淋巴样增生, 不规则血管, 内皮细胞增生, 墓碑状

Abstract: Angiolymphoid hyperplasia with eosinophilia is a rare benign neoplastic lesion, which is easily misdiagnosed. We reported a 55-year-old female patient with left occipital scalp neoplasm accompanied by pruritus for more than half a year. Pathological examination of skin lesions showed that the epidermis was generally normal. Dermal vascular endothelial cells proliferated, and the nuclei protruded toward the lumen, in the shape of tombstones. A large number of lymphocytes and eosinophils were infiltrated around the canal. Surgical resection was performed.

Key words: angiolymphoid hyperplasia with eosinophilia, irregular vessel, endotheliosis, tombstoned