中国麻风皮肤病杂志 ›› 2025, Vol. 41 ›› Issue (2): 123-126.doi: 10.12144/zgmfskin202502123

• 临床研究 • 上一篇    下一篇

慢Mohs显微描记术联合背阔肌肌皮瓣治疗躯干部巨大隆突性皮肤纤维肉瘤二例并文献复习

谢凯1,2,王红蕾1,2*,谢卫星1,2,王学庆1,2,曹楠1,2,张广亮1,2,武宜雷1,2   

  1. 1山东第一医科大学附属皮肤病医院，山东济南，250022；2山东省皮肤病性病防治研究所，山东济南，250022 *共同第一作者
  • 出版日期:2025-02-15 发布日期:2025-01-22

Slow Mohs micrographic surgery combined with latissimus dorsi myocutaneous flap for the treatment of giant dermatofibrosarcoma protuberants on the trunk: two cases report and literature review

XIE Kai1,2*, WANG Honglei1,2*, XIE Weixing1,2, WANG Xueqing1,2, CAO Nan1,2, ZHNG Guangliang1,2, WU Yilei1,2   

  1. 1 Hospital for Skin Diseases, Shandong First Medical University, Jinan 250022, China; 2 Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences, Jinan 250022, China *Co-first author
  • Online:2025-02-15 Published:2025-01-22

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摘要： 目的：明确慢Mohs显微描记术联合背阔肌肌皮瓣治疗上躯干部巨大隆突性皮肤纤维肉瘤的疗效。方法：对采用慢Mohs显微描记术联合背阔肌肌皮瓣治疗的隆突性皮肤纤维肉瘤2例患者进行回顾性分析。结果：2例患者经一期慢Mohs手术后均获得阴性病理切缘，术后创面分别为10 cm×13 cm、15 cm×15 cm。均给予二期设计背阔肌肌皮瓣修复原发缺损，继发缺损直接闭合修复。患者皮瓣均全部成活，创面一期愈合。结论：慢Mohs显微描记术是治疗隆突性皮肤纤维肉瘤一线选择，肿瘤切除后躯干部大面积创面可采用背阔肌肌皮瓣修复创面。

关键词: 隆突性皮肤纤维肉瘤, Mohs显微描记术, 背阔肌肌皮瓣

Abstract: Objective: To access the efficacy of slow Mohs micrographic surgery combined with latissimus dorsi myocutaneous flap in the treatment of giant dermatofibrosarcoma protuberans of the upper trunk. Methods: The two patients with protuberant dermatofibrosarcoma treated with slow Mohs micrographic surgery combined with latissimus dorsi myocutaneous flap Were retrospectively analyzed. Results: Both patients achieved negative pathological margins after the first-stage slow Mohs surgery. The postoperative wounds were 10 cm×13 cm and 15 cm×15 cm, respectively. Both were treated with secondary design of latissimus dorsi myocutaneous flaps to repair the primary defects, and the secondary defects were sutured directly. Both patients' flaps survived completely, and the wounds healed primarily. Conclusions: Slow Mohs micrographic surgery is a first-line choice for the treatment of dermatofibrosarcoma, and the latissimus dorsi myocutaneous flap can be used to repair large wound surfaces on the trunk after tumor resection.

Key words: dermatofibrosarcoma protuberans, Mohs micrographic surgery, latissimus dorsi myocutaneous flap