中国麻风皮肤病杂志 ›› 2025, Vol. 41 ›› Issue (10): 736-737.doi: 10.12144/zgmfskin202510736

• 病例报告 • 上一篇    下一篇

儿童结节型黏液水肿性苔藓一例

王涵1,2,刘宏杰1,2,吕小岩1,2   

  1. 1四川大学华西医院皮肤科,四川成都，610041； 2四川大学华西医院疾病分子网络前沿科学中心免疫炎症研究院皮肤病学研究室，四川成都，610041
  • 出版日期:2025-10-15 发布日期:2025-09-28

Pediatric nodular localized lichen myxedematosus: a case report

WANG Han1,2, LIU Hongjie1,2, LYU Xiaoyan1,2   

  1. 1 Department of Dermatology, West China Hospital, Sichuan University, Chengdu 610041, China; 2 Laboratory of Dermatology, Clinical Institute of Inflammation and Immunology, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu 610041, China
  • Online:2025-10-15 Published:2025-09-28

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摘要： 结节型局限性黏液水肿性苔藓临床罕见，全球儿童病例报道仅5例。本文报道1例6岁女童躯干、四肢多发肤色及淡黄色结节3年，皮损无自觉症状。组织病理及阿辛蓝染色示真皮胶原间大量黏蛋白沉积，排除青少年自愈型黏液水肿性苔藓等疾病后，诊断为结节型局限性黏液水肿性苔藓，未治疗，随访半年病情稳定。

关键词: 黏液水肿性苔藓, 儿童皮肤病, 黏蛋白痣

Abstract: Nodular localized lichen myxedematosus is clinically rare, with only 5 cases reported in children worldwide. We report a 6-year-old girl with multiple skin-colored and pale yellow nodules on the trunk and extremities for 3 years, without subjective symptoms. Histopathology and Alcian blue staining showed massive mucin deposition between dermal collagens. After excluding juvenile self-healing lichen myxedematosus and other diseases, the diagnosis of nodular localized lichen myxedematosus was made. No treatment was given, and the condition remained stable during a 6-month follow up.

Key words: nodular lichen myxedematosus, pediatric dermatology, mucinous nevus