中国麻风皮肤病杂志 ›› 2026, Vol. 42 ›› Issue (5): 361-363.doi: 10.12144/zgmfskin202605361

• 病例报告 • 上一篇    下一篇

溶脂针注射后偶发分枝杆菌感染一例

邹宇宁1*,黄艳春2*,陶家兴3,王康宁1,占萍3   

  1. 1江西中医药大学临床医学院，江西南昌，330004； 2江西省人民医院，江西南昌，330006； 3上海市第七人民医院皮肤科，上海，200137 *共同第一作者
  • 出版日期:2026-05-15 发布日期:2026-05-11

Mycobacterium fortuitum infection after lipolytic injection: a case report

ZOU Yuning1*, HUANG Yanchun2*, TAO Jiaxing3, WANG Kangning1, ZHAN Ping3   

  1. 1 School of Clinical Medicine, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China; 2 Jiangxi Provincial People's Hospital, Nanchang 330006, China; 3 Department of Dermatology, Shanghai Seventh People's Hospital, Shanghai 200137, China *Co-first authors
  • Online:2026-05-15 Published:2026-05-11

PDF (PC)

9

摘要： 偶发分枝杆菌为条件致病菌，近年医源性感染上升。本文患者因腹部注射点皮下硬结伴压痛13天来诊，自诉发病前2个月在某美容院行腹部皮下注射“溶脂针”减肥。通过蛋白飞行质谱、基因芯片和分子测序鉴定为偶发分枝杆菌，患者对利福平、乙胺丁醇过敏，阿米卡星治疗中出现耳毒性，最终采用莫西沙星联合克拉霉素口服并配合外科清创，治疗6个月痊愈，随访3年未复发。

关键词: 皮肤软组织感染, 偶发分枝杆菌, 溶脂针

Abstract: Mycobacterium fortuitum is an opportunistic pathogen, and iatrogenic infections caused by this bacterium have been on the rise in recent years. The patient in this study presented with subcutaneous induration and tenderness at abdominal injection sites for 13 days. She reported receiving abdominal subcutaneous injections of a “fat-dissolving injection” for weight loss at a beauty salon 2 months prior to the onset of symptoms. The pathogen was identified as Mycobacterium fortuitum using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry, gene chip, and molecular sequencing. The patient was allergic to rifampicin and ethambutol, and ototoxicity occurred during amikacin treatment. Finally, oral moxifloxacin combined with clarithromycin plus surgical debridement was adopted, and the patient recovered after 6 months of treatment with no recurrence during 3 years of follow-up.

Key words: cutaneous soft tissue infection, Mycobacterium fortuitum, fat-dissolving injection