中国麻风皮肤病杂志 ›› 2016, Vol. 32 ›› Issue (8): 474-476.

• 短篇论著 • 上一篇    下一篇

湖北十堰市360例过敏性皮肤病患者食物不耐受检测分析

陈婷婷，王润超，陈少秀，张霞，黄萍，赵红梅，王震，段德鉴   

  1. 湖北医药学院附属太和医院皮肤科湖北十堰， 442000
  • 出版日期:2016-08-15 发布日期:2018-12-29
  • 基金资助:
    段德鉴；E-mail：oldduan2000@126.com

Analysis of food intolerance testing in 360 patients with allergic dermatosis in Shiyan，Hubei province

CHEN Tingting, WANG Runchao, CHEN Shaoxiu, ZHANGg Xia, HUANG Ping, ZHAO Hongmei, WANG Zhen, DUAN Dejian.   

  1. Department of Dermatology, Taihe Hospital, Hubei University of Medicine, Shiyan 442000,China
  • Online:2016-08-15 Published:2018-12-29
  • Supported by:
    DUAN Dejian, E-mail:oldduan2000@126.com

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摘要： 目的：检测十堰市过敏性皮肤病患者14种食物血清特异性IgG抗体, 筛选相关不耐受食物。方法： 运用酶联免疫法对360例过敏性皮肤病患者进行特异性IgG抗体定量检测。结果：特异性IgG抗体检测总阳性率53.89%，未成年组阳性率达78.05%，明显高于成年组(46.76%)，差异有统计学意义(P<0.05)。按阳性率高低不耐受食物依次是鸡蛋（31.11%）、牛奶（11.94%）、鳕鱼（8.89%）；患者同时对2种或2种以上食物不耐受的比例达23.89%。结论：本地区常见不耐受食物为鸡蛋、牛奶及鳕鱼，且未成年更易出现不耐受现象。

关键词: 过敏原, 特异性IgG抗体, 过敏性皮肤病, 食物不耐受

Abstract: Objective: To detect the positivity rate of 14 kinds of specific immunoglobulin G antibodies (sIgG Abs) in the patients with allergic dermatosis in Shiyan, Hubei province, in order to determine the intolerant food. Method: sIgG Abs in 360 patients with allergic dermatosis was detected by enzyme-linked immunosorbent assay (ELISA). Results: The positivity rate was 53.89% in all patients and was 78.05% in younger patients, while the positivity rate in adults was 46.76%. The difference between the two groups was statistically significant (P<0.05). The most common intolerant food was egg (31.11%), followed by milk (11.94%) and codfish (8.89%). The positivity rate in the patients who were intolerant to 2 or more kinds of food was 23.89%. Conclusion: The common food allergens are egg, milk and codfish. The younger the patient is, the higher rate of food intolerance in the group of the patients.

Key words: allergen, specific IgG antibodies, allergic dermatosis, food intolerance