中国麻风皮肤病杂志 ›› 2017, Vol. 33 ›› Issue (8): 485-486.

• 临床研究 • 上一篇    下一篇

贝复新联合曲安奈德益康唑乳膏治疗面部湿疹临床研究

陈荣威  梁国雄  胡宝蝉  阙冬梅  杨娟   

  1. 广东医科大学附属中山陈星海医院/中山市陈星海医院皮肤性病科，中山，528415
  • 出版日期:2017-08-15 发布日期:2018-12-05

Efficacy of the rb-bFGF gel combined with compound triamcinolone acetonide and econazole nitrate cream in the treatment of facial eczema

CHEN Rongwei, LIANG Guoxiong, HU Baochan, QUE Dongmei, YANG Juan.   

  1. Department of Dermatology, The Affiliated Zhongshan Chenxinghai Hospital of Guangdong Medical University, Zhongshan 528415, China
  • Online:2017-08-15 Published:2018-12-05

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摘要： 目的：评价贝复新联合曲安奈德益康唑乳膏治疗面部湿疹的临床疗效及安全性。方法：107例患者随机分为治疗组（57例）和对照组（50例），治疗组外用贝复新联合曲安奈德益康唑乳膏，对照组仅外用曲安奈德益康唑乳膏。结果：治疗2周后，治疗组症状体征评分为1.23±1.65，明显低于对照组的2.22±2.14，差异有统计学意义(P＜0.05)。治疗组有效率为87.72%，高于对照组的70%，差异有统计学意义(P＜0.05)。两组患者均未见明显不良反应。结论：贝复新联合曲安奈德益康唑乳膏治疗面部湿疹优于单用曲安奈德益康唑乳膏。

关键词: 贝复新, 曲安奈德益康唑, 面部湿疹

Abstract: Objective: To assess the efficacy and safety of rb-bFGF gel combined with compound triamcinolone acetonide and econazole nitrate cream in the treatment of facial eczema. Methods: One hundred and seven patients with facial eczema were enrolled and randomly divided into the treatment group (57 patients) and control group (50 patients). The patients in the control group were treated with compound triamcinolone acetonide alone and the patients in the treatment group were treated with additional rb-bFGF gel. Results: After 2 weeks treatment, the total score of the signs and symptoms of the patients in the treatment group was 1.23±1.65, which was lower than that in the control group (2.22±2.14), with a significant difference (P<0.05). The effective rate in the treatment group was 87.72%, which was higher than that in the control group (70%), with a significant difference (P<0.05). There was no obvious adverse reactions in both groups of the patients. Conclusion: rb-bFGF gel combined with compound triamcinolone acetonide and econazole cream in the treatment of facial eczema is more effective than compound triamcinolone acetonide and econazole alone. 

Key words: rb-bFGF gel, triamcinolone acetonide and econazole nitrate, facial eczema