中国麻风皮肤病杂志 ›› 2018, Vol. 34 ›› Issue (2): 77-79.

• 论著 • 上一篇    下一篇

泼尼松联合沙利度胺治疗重度II型麻风反应患者的疗效评价

卢海洪   

  1. 广西壮族自治区亭凉医院皮肤科，广西南宁 530022
  • 出版日期:2018-02-15 发布日期:2018-12-05

Assessment of the efficacy of prednisone combined with thalidomide in the treatment of severe type-2 leprosy reactions

LU Haihong .   

  1. Department of Dermatology Tingliang Hospital, Guangxi 530022，China
  • Online:2018-02-15 Published:2018-12-05

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摘要： 目的：评价泼尼松联合沙利度胺治疗重度II型麻风反应患者的疗效。方法：重度II型麻风反应患者38例给予泼尼松30mg/d早晨顿服同时给予沙利度胺100mg/次，每日 3次，待症状控制后逐渐减量至停药，总疗程 4个月。结果：重度II型麻风反应患者痊愈率86.84％、显效率94.73％。结论：泼尼松联合沙利度胺治疗重度II型麻风反应患者疗效显著

关键词: 重度II型麻风反应, 沙利度胺, 泼尼松

Abstract: Objective: To assess the efficacy of prednisone combined with thalidomide in the treatment of severe type-2 leprosy reactions. Methods：Thirty patients with severe type-2 leprosy reaction were treated with prednisone, 30mg, once a day, and thalidomide, 100mg, three times a day. The drug was gradually reduced after symptoms were controlled, The total course was 4 months. Results: The recovery rate and effect rate were 86.84% and 94.73％. Conclusion: Prednisone combined with thalidomide is effective in the treatment of severe type-2 leprosy reaction.

Key words: severe II leprosy reaction, thalidomide, prednisone