Abstract: An infant presented with a round-like defect on the top of scalp when he was born. The diagnosis of aplasia cutis congenital (ACC) was made. ACC is a congenital disease with local or extensive skin defects as the main clinical manifestation, which can affect any part of the body, most commonly the scalp. The pathogenesis of ACC is still unclear, and it can be independently or accompanied by other genetic diseases. At present, the treatment methods of ACC mainly include conservative treatment and surgical treatment, but there are controversies. In this paper, a case of ACC was reported and relevant literature was reviewed to provide reference for clinical diagnosis and treatment.

Key words: aplasia cutis congenital, the scalp, neonate