Abstract: Skin aging can be divided into internal and external aging. Recent studies suggest that expect for ultraviolet-induced photoaging, many other factors are also involved in the skin aging process, and the adipose tissues also appear photoaging features. In addiation to the classic application, botulinum toxin type-A, cross-linked hyaluronic acid and polydioxanone thread also have centain anti-aging effects. The skin photoaging mechanisms, clinical manifestations and new progress in provention and treatment are reviewed in the article.