中国麻风皮肤病杂志 ›› 2019, Vol. 35 ›› Issue (8): 467-468.doi: 10.12144/zgmfskin201908467

• 论著 • 上一篇    下一篇

155例眼睑皮炎患者斑贴试验结果分析

周晓谦  王幼学  尼建义  杨竹生  杨秀敏   

  1. 首都医科大学附属北京同仁医院，北京，100730
  • 出版日期:2019-08-15 发布日期:2019-08-19
  • 通讯作者: 杨秀敏，E-mail：18811612180@163.com

Analysis of patch test in 155 cases with eyelid dermatitis

ZHOU Xiaoqian, WANG Youxue, NI Jianyi, YANG Zhusheng, YANG Xiumin   

  1. Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China
  • Online:2019-08-15 Published:2019-08-19
  • Contact: YANG Xiumin, E-mail: 18811612180@163.com

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摘要： 目的：明确眼睑皮炎的常见变应原。方法：回顾分析我院皮肤科2018年155例眼睑皮炎患者斑贴试验资料。结果：155例眼睑皮炎患者中85例斑贴试验阳性, 总阳性率为54.8%。其中对1项过敏原反应阳性者27例（31.8%），2项过敏原阳性者19例（22.4%），3项过敏原阳性者14例（16.5%），4项及以上过敏原阳性者25例（29.4%）。阳性率较高的前3位过敏原依次是：硫酸镍（24例，9.4%），甲基异噻唑啉酮（24例，9.4%），纺织染料混合物（14例，5.5%）。＜20岁，20～39，40～59，≥60岁患者斑贴试验阳性率分别为37.5%，54.2%，65.0%，18.2%，不同年龄组阳性率结果具有统计学意义(χ2=8.483，P＜0.05）。结论：甲基异噻唑啉酮、硫酸镍、纺织染料混合物是眼睑皮炎患者最常见的变应原，变应原阳性率的高低与患者的年龄有一定关联。

关键词: 眼睑皮炎, 斑贴实验

Abstract: Objective: To determine the common allergens of eyelid dermatitis. Methods: The patch test results of 155 patients with eyelid dermatitis diagnosed in 2018 were retrospectively analyzed. Results: Of 155 patients with eyelid dermatitis, the  patch test was positive in 85 patients (54.8%). Twentyseven cases (31.8%) were positive to one allergen, 19 (22.4%) to two allergens, 14 (16.5%) to three allergens, and 25 cases (29.4%) to four allergens or more. The first three allergens with high positivity rate were nickel sulfate (24 cases, 9.4%), methylisothiazolinone (24 cases, 9.4%) and textile dye mixture (14 cases, 5.5%). The positivity rates in  different age groups of <20, 20-39, 40-59, ≥60 years old were 37.5%，54.2%，65.0% and 18.2%, with a significant difference among the four groups (P＜0.05). Conclusion: Methylisothiazolinone, nickel sulfate, textile dye mixture, cobalt chloride are the most common allergens in the patients with eyelid dermatitis in our hospital, and the positivity rate of allergens is correlated with the age.

Key words: eyelid dermatitis, patch test