中国麻风皮肤病杂志 ›› 2019, Vol. 35 ›› Issue (12): 707-709.doi: 10.12144/zgmfskin201912707

• 论著 • 上一篇    下一篇

82例女性外阴慢性单纯性苔藓患者斑贴试验分析

高小曼，李明，刘琬，杨敏，常建民   

  1. 北京医院皮肤科，国家老年医学中心，北京，100730
  • 出版日期:2019-12-15 发布日期:2019-12-24
  • 通讯作者: 常建民，E-mail：changjianmin@medmail.com.cn

Analysis of patch test on 82 cases of vulvar lichen simplex chronicus

GAO Xiaoman, LI Ming, LIU Wan, YANG Min, CHANG Jianmin   

  1. Department of Dermatology, Beijing Hospital, National Center of Gerontology, Beijing 100730, China
  • Online:2019-12-15 Published:2019-12-24
  • Contact: CHANG Jianmin，E-mail：changjianmin@medmail.com.cn

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摘要： 目的：检测女性外阴慢性单纯性苔藓（VLSC）患者接触性过敏原情况。方法：对2017年3月至2018年3月就诊于我科的VLSC患者行60项变应原斑贴试验。结果：82例患者中53例患者(64.73%)呈阳性反应。60项变应原中共有29种变应原呈阳性反应，其中阳性率排前三位变应原种类为金属盐（32例）、防腐剂（18例）、芳香剂（16例），阳性率排前四位变应原分别为硫酸镍（24例）、氯化钴（15例）、芳樟醇氢过氧化物（10例）、甲基异噻唑啉酮（6例）。结论：VLSC可能与接触过敏原有关，金属盐、防腐剂、芳香剂是最常见变应原种类。

关键词: 女性外阴慢性单纯性苔藓, 斑贴试验, 变应原

Abstract: Objective: To detect the contact allergens in patients with vulvar lichen simplex chronicus (VLSC). Methods: The patients with VLSC visited in our clinic from March 2017 to March 2018 were  performed  patch testing including 60 allergens. Results: A total of 82 patients with VLSC were enrolled into the study, 53 (64.73%) had at least one positive patch test. The first three positive allergens were metals (32 cases), preservative(18 cases), and perfume(16 cases). The most frequent allergen was nickel sulphate (24 cases), followed by cobalt chloride (15 cases), hydroperoxides of linalool (10 cases) and methylisothiazolinone (6 cases). Conclusion: The most common positive allergens of VLSC were metals,preservative and perfume. 

Key words: vulvar lichen simplex chronicus, patch test, allergens