中国麻风皮肤病杂志 ›› 2020, Vol. 36 ›› Issue (2): 104-105.doi: 10.12144/zgmfskin202002104

• 病例报告 • 上一篇    下一篇

不典型结节性黄瘤一例

唐新月 唐教清 王琳   

  1. 四川大学华西医院，成都，610041
  • 出版日期:2020-02-15 发布日期:2020-03-18
  • 通讯作者: 王琳，E-mail: lkzwl@126.com

Tuberous xanthoma with atypical clinical manifestation: a case report

TANG Xinyue, TANG Jiaoqing, WANG Lin   

  1. West China Hospital, Sichuan University, Chengdu 610041, China
  • Online:2020-02-15 Published:2020-03-18
  • Contact: WANG Lin, E-mail: lkzwl@126.com

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摘要： 患者，女，56岁。右腹股沟、骶部丘疹和肿块32年。皮肤组织病理：组织细胞及泡沫样细胞浸润，较多多核巨细胞及不典型Touton细胞散在其中。免疫组化染色示浸润细胞表达CD68-PGM1、CD68-KP1和CD163。诊断：结节性黄瘤。给予手术及降脂治疗。

关键词: 结节性黄瘤, Touton细胞

Abstract: A 56-year-old female presented with multiple papules and nodules on her right groin and sacral region for 32 years. Histopathological examination showed numerous epithelioid histiocytes and foam-like cells infiltrating in lower dermis, with scattered multinucleated giant cells and atypical Touton cells. Immunohistochemistry showed the tumor cells were positive for CD68-PGM1, CD68-KP1 and CD163. The diagnosis of tuberous xanthomas was made. The patient was treated with surgery and lipid lowering therapy.

Key words: tuberous xanthomas, Touton cells