中国麻风皮肤病杂志 ›› 2020, Vol. 36 ›› Issue (3): 174-175.doi: 10.12144/zgmfskin202003174

• 病例报告 • 上一篇    下一篇

皮肤上皮样血管瘤性结节一例

王英1,李思彤1,赵子东2,白彦萍1,崔勇1,郑占才1   

  1. 1中日友好医院皮肤科，北京，100029；2巴林左旗蒙医中医医院皮肤科，赤峰，025450
  • 出版日期:2020-03-15 发布日期:2020-03-30
  • 通讯作者: 郑占才，E-mail: drzhengzhancai@163.com

Cutaneous epithelioid angiomatous nodule: a case report

WANG Ying1, LI Sitong1, ZHAO Zidong2, BAI Yanping1, CUI Yong1, ZHENG Zhancai1   

  1. 1 Department of Dermatology, China-Japan Friendship Hospital, Beijing 100029, China; 2 Department of Dermatology, Ba Lin Zuo Qi Meng Yi Traditional Chinese Medical Hospital, Chifeng 025450, China
  • Online:2020-03-15 Published:2020-03-30
  • Contact: ZHENG Zhancai, E-mail: drzhengzhancai@163.com

PDF (PC)

114

摘要： 皮肤上皮样血管瘤性结节是一种少见的良性皮肤血管增生性疾病，临床表现为单发或多发的红色或紫红色的斑块、结节，好发于躯干及四肢,本文报道一例。患者，女，47岁。背部红色结节3个月伴轻微瘙痒，组织病理示结节位于真皮浅层，周围无包膜,由上皮样血管内皮细胞增生形成，无明显异型性，大量管腔样结构形成，免疫组化示：CD31(+), CD34(+), D2-40(+), Fli-1(+), KP-1(+), Ki-67(20%+),溶菌酶(+)。诊断：皮肤上皮样血管瘤性结节。治疗：行手术切除，随访至今2年未复发。

Abstract: Cutaneous epithelioid angiomatous nodule (CEAN) is a rare, benign, vascular hyperplasia. It clinically presents as single or multiple, reddish to bluish plaques or nodules, mainly on the trunk and extremities. We reported a 47-year-old female who presented with a nodule on the back for 3 months with mild itching. Biopsy showed the nodule was in the dermis, well-circumscribed, composed of epithelioid cells without heterocyst and a large number of lumen structures were formed. Immunohistochemistry demonstrated positive for CD31, CD34, D2-40, Fli-1, KP-1, Ki-67 (presented a level proliferation index of 20％) and positive lysozyme. The diagnosis of CEAN was made and the nodule was removed with no recurrence for 2 years.