中国麻风皮肤病杂志 ›› 2020, Vol. 36 ›› Issue (4): 239-241.doi: 10.12144/zgmfskin202004239

• 病例报告 • 上一篇    下一篇

以色素性紫癜性皮病为表现的蕈样肉芽肿一例

陶荣,涂平,汪旸,仲少敏   

  1. 北京大学第一医院皮肤科，北京市皮肤病分子诊断重点实验室，国家皮肤与免疫疾病临床医学研究中心，北京，100034
  • 出版日期:2020-04-15 发布日期:2020-04-27
  • 通讯作者: 仲少敏，E-mail: zhongshaomin@sina.com

Mycosis fungoides manifested as pigmented purpuric dermatoses

TAO Rong, TU Ping, WANG Yang, ZHONG Shaomin   

  1. Department of Dermatology(and Venerology), Peking University First Hospital, Beijing Key Laboratory of  Molecular Diagnosis on Dermatoses, National Clinical Research Center for Skin and Immune Diseases, Beijing 100034, China
  • Online:2020-04-15 Published:2020-04-27
  • Contact: pigmented purpuric dermatoses; mycosis fungoides

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摘要： 患者，男，70岁。左下肢皮疹10余年，泛发全身伴痒3个月。皮肤科检查：四肢为主的广泛对称的紫癜性暗红色斑片、斑块，躯干散在的暗红色斑疹表面可见明显鳞屑。皮肤组织病理示符合蕈样肉芽肿诊断。患者给予重组人干扰素α2b，肌注，300MIU，1周3次，甲氨蝶呤10 mg，1周1次，同时配合窄谱中波紫外线（NB-UVB）1周3次治疗。经1年余治疗后患者明显好转。

关键词: 色素性紫癜性皮病, 蕈样肉芽肿

Abstract:  A 70-year-old male presented with erythema in the left crus for more than 10 years, and extended to all over the body with pruritus for 3 months. Dermatological examination showed widespread, symmetric, dull red patches and plaques on the limbs. The lesions on the trunk were scales. Histopathological features were in accordance with the diagnosis of mycosis fungoides. The patient was treated with recombinant interferon α2b intromuscular injection, 300MIU, three times a week, methotrexate 10 mg, once a week, and NB-UVB once a week. After treatment for one year,  the lesions were  improved markedly.

Key words: pigmented purpuric dermatoses, mycosis fungoides