中国麻风皮肤病杂志 ›› 2020, Vol. 36 ›› Issue (12): 747-749.doi: 10.12144/zgmfskin202012747

• 病例报告 • 上一篇    下一篇

多发性骨髓瘤伴坏疽性脓皮病一例

王晓宇1,李薇薇1,王媛1,鞠延娇1,徐敏丽1,马春燕2,谢志强1,张春雷1   

  1. 1北京大学第三医院皮肤科，北京，100191；2北京京城皮肤病医院皮肤科，北京，100085
  • 出版日期:2020-12-15 发布日期:2020-12-04
  • 通讯作者: 李薇薇，E-mail: liweiwei792002@sina.com

Gangrenous pyoderma complicated with multiple myeloma: a case report

WANG Xiaoyu1, LI Weiwei1, WANG Yuan1, JU Yanjiao1, XU Minli1, MA Chunyan2, XIE Zhiqiang1, ZHANG Chunlei1   

  1. 1 Department of Dermatology, Peking University Third Hospital, Beijing 100191, China; 
    2 Department of Dermatology, Beijing Jingcheng Dermatology Hospital, Beijing 100085, China
  • Online:2020-12-15 Published:2020-12-04
  • Contact: LI Weiwei, E-mail: liweiwei792002@sina.com

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摘要： 患者，女，71岁。双下肢反复溃疡伴疼痛20个月余。皮损组织病理检查符合坏疽性脓皮病。免疫球蛋白固定电泳示IgGκ链免疫电泳单克隆区带。骨髓穿刺结果示骨髓增生活跃，见异常浆细胞，幼稚浆细胞占29.5%。诊断：多发性骨髓瘤伴坏疽性脓皮病。

关键词: 坏疽性脓皮病, 多发性骨髓瘤

Abstract: A 71-year-old female presented with ulcer on both lower limbs with pain for more than 20 months. The biopsy features were in accordance with the diagnosis of pyoderma gangraenosum. Immunoelectrophoresis showed monoclonal bands of IgGκ monoclone brand. Bone marrow puncture showed active myelodysplasia, abnormal plasma cells, immature plasma cells accounted for 29.5%. The diagnosis of multiple myeloma with pyoderma gangraenosum was made.

Key words: pyoderma gangraenosum, multiple myeloma