中国麻风皮肤病杂志 ›› 2021, Vol. 37 ›› Issue (4): 245-247.doi: 10.12144/zgmfskin202104245

• 临床研究 • 上一篇    下一篇

液氮冷冻与Q开关激光治疗脂溢性角化病的疗效比较

秦晓庆,李烁,葛玉婷,赵孙秀   

  1. 南通市第六人民医院皮肤科，江苏南通，226011
  • 出版日期:2021-04-15 发布日期:2021-04-07
  • 通讯作者: 秦晓庆，E-mail: pifukeqin@163.com

Comparation of efficacy of liquid nitrogen cryotherapy and Q-switched laser in the treatment of seborrheic keratosis

QIN Xiaoqing, LI Shuo, GE Yuting, ZHAO Sunxiu   

  1. Department of Dermatology, Nantong Sixth People's Hospital the Skin Department, Nantong 226001, China
  • Online:2021-04-15 Published:2021-04-07
  • Contact: QIN Xiaoqing, E-mail: pifukeqin@163.com

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摘要： 目的：比较液氮冷冻与Q开关激光治疗脂溢性角化病的临床疗效。方法：选取2017年6月至2020年2月间我科就诊的脂溢性角化病患者，随机分为液氮冷冻组和Q开关激光治疗组。结果：共治疗170例患者，其中液氮冷冻组85例245枚皮损痊愈238枚（97.14%），显效7枚（2.86%），总有效率为100%，治疗后6个月继发性色素沉着12枚（4.90%）；Q开关激光治疗85例218枚皮损痊愈213枚（97.71%），显效5枚（2.29%），总有效率为100%，治疗后6个月继发性色素沉着8枚（3.67%）。两组间痊愈率、总有效率及色素沉着率比较，差异均无统计学意义（均P>0.05）。结论：液氮冷冻与Q开关激光治疗脂溢性角化病的临床疗效相当，均未见明显不良反应。

关键词: 脂溢性角化病, 液氮冷冻, Q开关激光

Abstract: Objective: To compare the efficacy of liquid nitrogen cryotherapy and Q-switched laser in the treatment of seborrheic keratosis. Methods: The patients with seborrheic keratosis from June 2017 to February 2020 in our hospital were randomly divided into liquid nitrogen cryotherapy group and Q-switched laser group. Results: A total of 170 patients were enrolled, including 85 cases with 245 lesions in the liquid nitrogen cryotherapy group and 85 cases with 218 lesions in the Q-switched laser group. In liquid nitrogen cryotherapy group, 238 lesions (97.14%) were cured, 7 (2.86%) were markedly effective, the total effective rate was 100%, 12 lesions (4.9%) left pigmentation after six months of treatment. In the Q-switched laser group, 213 lesions (97.71%) were cured, 5 (2.29%) were markedly effective, the total effective rate was 100%, 8 lesions (3.67%) left pigmentation after six months of treatment. There was no significant difference of recovery rate, total effective rate and the occurrence rate of pigmentation (Ps>0.05). Conclusion: The liquid nitrogen cryotherapy and Q-switched laser in the treatment of seborrheic keratosis are equally effective with no obvious adverse reaction.

Key words: seborrheic keratosis, liquid nitrogen cryotherapy, Q-switched laser