中国麻风皮肤病杂志 ›› 2021, Vol. 37 ›› Issue (7): 454-455.doi: 10.12144/zgmfskin202107454

• 病例报告 • 上一篇    下一篇

深部良性纤维组织细胞瘤一例

李思彤1,2,吴亚桐2,王英2,白彦萍2   

  1. 1北京协和医学院研究生院中日友好临床医学研究所，北京，100029；2中日友好医院皮肤性病科，北京，100029
  • 出版日期:2021-07-15 发布日期:2021-06-25
  • 通讯作者: 白彦萍，E-mail: zhi@tsinghua.edu.cn

Deep ‘benign’ fibrous histiocytoma: a case report

LI Sitong1,2, WU Yatong2, WANG Ying2, BAI Yanping2   

  1. 1 Department of Dermatology, China-Japan Friendship Hospital, Beijing 100029, China; 
    2 Clinical Institute of China-Japan Friendship Hospital, Peking Union Medical College Graduate School, Beijing 100029, China
  • Online:2021-07-15 Published:2021-06-25
  • Contact: BAI Yanping, E-mail: zhi@tsinghua.edu.cn

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摘要： 深部“良性”纤维组织细胞瘤是一种罕见的纤维组织细胞肿瘤，好发于四肢，本文报道1例。患者，女，56岁，左前臂无痛性皮下肿物4年，组织病理示境界清楚的单发性圆形皮下肿物，约1.8 cm×1.3 cm×0.6 cm，周围有纤维性假包膜，肿瘤细胞丰富，呈梭形或类圆形，编织状致密排列，细胞无明显异型性。 免疫组化：CD34(+)， αSMA(部分+)， Desmin(-)， Stat6（-），KP-1(-)，Ki-67(2%+)。诊断：深部良性纤维组织细胞瘤。治疗：手术完整切除肿瘤。随访16个月未见复发。

Abstract: Deep “benign” fibrous histiocytoma(DBFH)is a rare benign fibrous tumour which most commonly arise in subcutaneous tissue. We report a 56-year-old female who presented with a painless nodule on her left arm for 4 years. Histopathology examination showed a solitary oval and well-defined borders subcutaneous tumour with fibrous pseudocapsule. The dimensions of tumour were about 1.8 cm×1.3 cm×0.6 cm, composed of bland ovoid to spindle cells arranged in a storiform pattern and with no atypia. Immunohistochemistry demonstrated CD34 positive, αSMA partially positive, and non-expression for Desmin, Stat6 and KP-1. Ki-67 presented a level of proliferation index of about 2%. The diagnosis of DBFH was made and the nodule was completely excised with no recurrence for 16 months.