中国麻风皮肤病杂志 ›› 2023, Vol. 39 ›› Issue (5): 362-363.doi: 10.12144/zgmfskin202305362

• 病例报告 • 上一篇    下一篇

恶性梅毒一例

于学红1,王牧原2,孙晓静1   

  1. 1山东大学附属威海市立医院，山东威海，264200；
    2山东第一医科大学，山东济南，250000
  • 出版日期:2023-05-15 发布日期:2023-05-16

Malignant syphilis: a case report

YU Xuehong1, WANG Muyuan2, SUN Xiaojing1   

  1. 1 Department of Dermatology, Weihai Municipal Hospital, Cheeloo College of Medicine,Shandong University, Weihai 264200, China;
    2 Shandong First Medical University, Jinan 250000, China
  • Online:2023-05-15 Published:2023-05-16

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摘要： 患者，女,52岁。躯干、四肢皮疹伴头痛、发热1个月。皮肤科检查：躯干、四肢多发性丘疹、结节，伴触痛，部分皮疹中心结痂。梅毒血清学检查：TPPA阳性 , TRUST滴度1∶64。患者经苄星青霉素治疗后，TRUST滴度下降及皮损消退均非常缓慢。治疗18个月后，皮损呈淡褐色萎缩性瘢痕。TRUST滴度1∶2。

关键词: 恶性梅毒, 结节性皮损

Abstract: A 52-year-old female presented with rash on the trunk and limbs with fever and headache for 1 month. Dermatology showed multiple papules and nodes on the trunk and limbs with tenderness. Scab was seen in the center of some rashes.TPPA was positive and TRUST titer was 1∶64. The patient was treated with benzylpenicillin, but the decrease degree of TRUST titre and the skin lesions improved very slowly. After treated for 18 months, the lesions turned brown atrophic scars and TRUST titer decreased to 1∶2.

Key words: malignant syphilis, nodular skin lesions