中国麻风皮肤病杂志 ›› 2024, Vol. 40 ›› Issue (4): 283-285.doi: 10.12144/zgmfskin202404283

• 病例报告 • 上一篇    下一篇

巴西诺卡菌感染所致的原发性皮肤诺卡菌病一例

庄凯文,冉昕,游紫梦,孙计同,冉玉平   

  1. 四川大学华西医院皮肤科，四川成都，610041
  • 出版日期:2024-04-15 发布日期:2024-03-26

Primary cutaneous nocardiosis caused by Nocardia brasiliensis: a case report

ZHUANG Kaiwen, RAN Xin, YOU Zimeng, SUN Jitong, RAN Yuping   

  1. Department of Dermatology, West China Hospital, Sichuan University, Chengdu 610041, China
  • Online:2024-04-15 Published:2024-03-26

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摘要： 原发性皮肤诺卡菌病是一种由诺卡菌属直接感染皮肤及皮下组织引起的少见感染性疾病，临床表现多样，极易被误诊。本例患者左前臂红斑、结节、脓肿及溃疡，表面大量脓性分泌物2周。活检组织培养长出黄白色菌落，鉴定为巴西诺卡菌。患者口服复方磺胺甲噁唑治疗50天后痊愈。

关键词: 原发性皮肤诺卡菌病, 巴西诺卡菌, 复方磺胺甲噁唑

Abstract: Primary cutaneous nocardiosis is a rare infectious disease caused by Nocardia species directly infected skin and subcutaneous tissue. The clinical manifestations are varied, and it is easy to be misdiagnosed. A patient presented with erythema, nodules, abscesses and ulcers on the left forearm with a large amount of purulent discharge for 2 weeks. Cultures of biopsy samples grew yellow-white colonies that were identified as Nocardia brasiliensis. The patient recovered after 50 days of oral treatment with trimethoprim-sulfamethoxazole (TMP-SMX).

Key words: primary cutaneous nocardiosis, Nocardia brasiliensis, TMP-SMX