中国麻风皮肤病杂志 ›› 2024, Vol. 40 ›› Issue (7): 508-510.doi: 10.12144/zgmfskin202407508

• 病例报告 • 上一篇    下一篇

阿布昔替尼成功治疗掌跖脓疱病一例

高鑫1,2,李梅2,解燕2,燕鹏荣2,赵国伟2   

  1. 1山东第二医科大学临床医学院，山东潍坊，261000；2淄博市中心医院，山东淄博，255000
  • 出版日期:2024-07-15 发布日期:2024-06-12

Palmoplantar pustulosis successfully treated with abrocitinib: a case report

GAO Xin1,2, LI Mei2, XIE Yan2, YAN Pengrong2, ZHAO Guowei2   

  1. 1 School of Clinical Medicine, Shandong Second Medical University, Weifang 261000, China; 2 Department of Dermatology, Zibo Central Hospital, Zibo 255000, China
  • Online:2024-07-15 Published:2024-06-12

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摘要： 本文报道阿布昔替尼成功治疗掌跖脓疱病一例并复习相关文献。该患者双手足反复脓疱、脱屑伴瘙痒1年，给予依奇珠单抗疗效不佳，调整为阿布昔替尼100 mg每日一次，治疗3个月皮损消退，随访半年未复发。

关键词: 掌跖脓疱病, 阿布昔替尼

Abstract: We report a case of palmoplantar pustulosis successfully treated with abrocitinib and review the related literature. The patient presented with repeated pustules, desquamation and pruritus on both hands and feet for 1 year. The patient had a poor response to eculizumab and was switched to abrocitinib 100 mg once daily. The skin lesions subsided after 3 months of treatment, and there was no recurrence during the follow-up of half a year.

Key words: palmoplantar pustulosis, abrocitinib