中国麻风皮肤病杂志 ›› 2024, Vol. 40 ›› Issue (8): 572-574.doi: 10.12144/zgmfskin202408572

• 病例报告 • 上一篇    下一篇

组织细胞吞噬性脂膜炎一例

李海珍,王宝庭,任辉邦,祁英   

  1. 青海省人民医院皮肤科，青海西宁，810000
  • 出版日期:2024-08-15 发布日期:2024-07-29

Cytophagic histiocytic panniculitis: a case report

LI Haizhen, WANG Baoting, REN Huibang, QI Ying   

  1. Department of Demtology, Qinghai Provincial People's Hospital, Xining  810000, China
  • Online:2024-08-15 Published:2024-07-29

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摘要： 组织细胞吞噬性脂膜炎(CHP)是一种罕见的临床疾病，以皮下脂肪组织的结节性小叶性脂膜炎为特征，本文报道1例。患者，男，56岁，双侧下肢及上肢反复出现疼痛性红斑、结节，伴发热、白细胞异常升高、周身乏力，抗生素治疗无效。病理活检示真皮可见“豆袋细胞”，最终明确诊断组织细胞吞噬性脂膜炎，给予糖皮质激素治疗后患者皮疹及症状迅速改善。

关键词: 组织细胞吞噬性脂膜炎, 皮下脂膜炎样T细胞淋巴瘤, 结节性脂膜炎, Weber Christian病

Abstract: Cytophagic histiocytic panniculitis (CHP) is a rare clinical disease characterized by nodular lobular panniculitis of subcutaneous adipose tissue. A 56-year-old male presented with recurrent painful erythema and nodules on both lower and upper limbs, with fever, abnormal increase in white blood cells, and overall weakness. Antibiotic treatment was ineffective. Pathological biopsy showed the presence of “beanbag cells” in the dermis, ultimately leading to a definitive diagnosis of cytophagic histiocytic panniculitis. After glucocorticoid treatment, the patient's rash and symptoms rapidly improved.

Key words: cytophagic histiocytic panniculitis, subcutaneous panniculitis-like T-cell lymphoma, nodular panniculitis, Weber Christian Disease