中国麻风皮肤病杂志 ›› 2025, Vol. 41 ›› Issue (1): 23-28.doi: 10.12144/zgmfskin202501023

• 论著 • 上一篇    下一篇

2013-2023年广安市HIV感染者及AIDS患者死亡病例分析

田彩虹1，秦小佳1，张军1，龚毅2，赵智蓉3   

  1. 1 广安市疾病预防控制中心，四川广安，638000；2 四川省疾病预防控制中心，四川成都，610000；3 昆明市第三人民医院，云南昆明，650200
  • 出版日期:2025-01-15 发布日期:2024-12-23

Analysis of death cases of HIV infections and AIDS patients in Guang'an from 2013 to 2023

TIAN Caihong1, QIN Xiaojia1, ZHANG Jun1, GONG Yi2, ZHAO Zhirong3   

  1. 1 Guang'an Disease Prevention and Control Center, Guang'an 638000, China; 2 Sichuan Provincial Disease Prevention and Control Center, Chengdu 610000, China; 3 Kunming Third People's Hospital, Kunming 650200, China
  • Online:2025-01-15 Published:2024-12-23

PDF (PC)

52

摘要： 收集2013-2023年国家艾滋病综合防治信息系统报告的广安市HIV/AIDS病例资料，运用Logistic回归模型分析HIV/AIDS病例死亡的影响因素。结果示广安市2013-2023年累计报告HIV/AIDS病例8803例，死亡2489例，病死率为28.27%。死亡病例中，AIDS占61.91%，男性占86.86%，确诊年龄在55岁及以上占68.62%，农民占72.32%，有配偶占55.56%，小学以下文化程度占74.25%，异性性传播占95.22%，医疗机构来源占73.04%，首次CD4+T淋巴细胞未查者和小于200个/μL占62.43%，未行抗病毒治疗(antiretroviral therapy，ART)和ART不及时者占66.05%。多因素Logistic回归分析结果显示，HIV、女性、有配偶、来源于非医疗机构、确诊年龄＜35岁、治疗及时的病例死亡概率较低；文化程度为小学及以下、确诊年龄≥55岁、首次就诊未检查CD4+T淋巴细胞、未治疗的病例死亡概率较高。不论是HIV感染者还是AIDS患者，治疗组存活时长显著高于未治疗组（P＜0.05）。

关键词: 获得性免疫缺陷综合征, 死亡病例特征, 抗病毒治疗

Abstract: The data came from the case information of HIV/AIDS cases in Guang'an City reported by the National AIDS Comprehensive Prevention and Control Information System (NACIS) from 2013 to 2023. The influencing factors of deaths of HIV/AIDS cases were analysed by using logistic regression model. The results showed there were 8803 cases of HIV/AIDS in Guang'an City from 2013 to 2023, with 2489 deaths, the case-fatality rate was 28.27%. Of the deaths, AIDS accounted for 61.91%, males for 86.86%, diagnoses at age 55 and above for 68.62%, farmers for 72.32%, individuals with spouses for 55.56%, education levels below primary school for 74.25%, heterosexual transmission for 95.22%, medical institutions for 73.04%, first CD4+ T lymphocyte counts not examined or less than 200 cells/μL for 62.43%, and those not receiving antiretroviral therapy (ART) or with delayed ART for 66.05%. Results from the multivariate Logistic regression analysis showed that HIV infection, being female, spouse, being from non-medical institutions, age at diagnosis <35 years old and timely treatment were associated with lower probability of death. Cases with education level of primary school or below, age at diagnosis ≥55, without CD4+T lymphocyte examination at the first visit, and untreated had a higher probability of death. Both HIV-infected individuals and AIDS patients in the treatment group had significantly longer survival times than those in the untreated group (P<0.05).

Key words: acquired immunodeficiency syndrome, characteristics of death cases, antiviral treatment