中国麻风皮肤病杂志 ›› 2025, Vol. 41 ›› Issue (5): 366-367.doi: 10.12144/zgmfskin202505366

• 病例报告 • 上一篇    下一篇

播散性皮肤痛风结节一例

陈慧苑,吴洁,朱雨云,冯晓琳   

  1. 广西医大开元埌东医院皮肤科，广西南宁，530021
  • 出版日期:2025-05-15 发布日期:2025-05-15

Disseminated cutaneous tophi: a case report

CHEN Huiyuan, WU Jie, ZHU Yuyun, FENG Xiaolin   

  1. Department of Dermatology, Langdong Hospital of Guangxi Medical University, Nanning 530021, China
  • Online:2025-05-15 Published:2025-05-15

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摘要： 播散性皮肤痛风结节发病与高尿酸血症密切相关，本文报道一例。患者，男，45岁，四肢、躯干多发结节3年，双下肢溃疡半年，尿酸 588 μmol/L，病理特点符合皮肤痛风结节。结合临床诊断为播散性皮肤痛风结节，予非布司他20 mg/d治疗并严格控制饮食，1个月后随访，复查血尿酸455 μmol/L，结节缩小，部分溃疡愈合。

关键词: 痛风, 皮肤痛风结节

Abstract: Disseminated cutaneous tophi is related to hyperuricemia. In this paper a patient dignosed as disseminated cutaneous tophi was reported. A 45-year-old man presented with multiple nodules on the limbs and trunk for 3 years and ulcers on both lower limbs for half a year. The uric acid was 588 μmol/L, and the pathological features were incorrdance with gouty nodules. The patient was diagnosed with disseminated cutaneous tophi and treated with febuxostat 20 mg/d and strict diet control. One month later, the blood uric acid level decreased to 455 μmol/L, the nodules had become smaller, and some ulcers were healed.

Key words: gout, cutaneous tophi