中国麻风皮肤病杂志 ›› 2025, Vol. 41 ›› Issue (6): 445-447.doi: 10.12144/zgmfskin202506445

• 病例报告 • 上一篇    下一篇

卡瑞利珠单抗致反应性皮肤毛细血管增生症一例

李婵,宋亚丽   

  1. 山东省公共卫生临床中心皮肤科，山东济南，250000
  • 出版日期:2025-06-15 发布日期:2025-05-23

Reactive cutaneous capillary endothelial proliferation induced by camrelizumab: a case report

LI Chan, SONG Yali   

  1. Department of Dermatology, Shandong Public Health Clinical Center, Jinan 250000, China
  • Online:2025-06-15 Published:2025-05-23

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摘要： 本文报道卡瑞利珠单抗免疫相关不良反应反应性皮肤毛细血管增生症一例。患者，男，56岁。因右肺腺癌并多部位转移，应用多西他赛、卡铂及卡瑞利珠单抗治疗5个周期后，头部、躯干皮肤出现数个增生性红色丘疹、结节，摩擦后易破溃、出血。诊断为反应性皮肤毛细血管增生症。给予手术切除、液氮冷冻治疗。术后1年随访，患者头部切口愈合良好，躯干皮损消退。

关键词: 反应性皮肤毛细血管增生症, 卡瑞利珠单抗

Abstract: We report a case of cutaneous capillary endothelial proliferation, a reaction to an immune-related adverse reaction of camrelizumab. A 56-year-old male presented with red papules scattered on the head and trunk with. The patient had right lung adenocarcinoma with metastases to multiple sites. After 5 cycles of treatment with docetaxel, carboplatin and camrelizumab, several proliferative red papules and nodules appeared on the skin of the head and trunk, which were prone to rupture and bleeding after friction. The patient was diagnosed with reactive cutaneous capillary endothelial proliferation and treated with surgical resection and liquid nitrogen cryotherapy at 1-year follow-up, the patient's head incision healed well and the trunk lesions subsided.

Key words: reactive cutaneous capillary endothelial proliferation, camrelizumab