中国麻风皮肤病杂志 ›› 2016, Vol. 32 ›› Issue (1): 7-10.

• 论著 • 上一篇    下一篇

疣状瓶霉所致着色芽生菌病1例

夏 杨1,2于长平1 王淑芬1 卢宪梅1张艳芳1 孙勇虎1 刘 红1 张福仁1   

  1. 1. 山东省皮肤病性病防治研究所，济南，250022 2. 济南大学山东省医学科学院医学与生命科学学院，济南，250062
  • 出版日期:2016-01-15 发布日期:2018-12-13
  • 通讯作者: 张福仁，Email: zhangfuren@hotmail.com?

Chromoblastomycosis caused by Phialophora verrucosa: a case report

XIA Yang, YU Chang-ping, ZHANG Fu-ren, et al.   

  1. 1.Shandong Provincial Institute of Dermatology and Venereology, Jinan 250022, China 2.School of Medicine and Life Sciences, University of Jinan-Shandong Academy of Medical Sciences, Jinan 250062, China
  • Online:2016-01-15 Published:2018-12-13
  • Contact: ZHANG Fu-ren, Email: zhangfuren@hotmail.com

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摘要： 患者，男，60 岁。右手腕红斑结痂，缓慢扩展16年。皮肤科检查：右手腕4 cm×6 cm环形暗红斑，皮疹边界清晰，覆有渗出性痂。真菌镜检见棕黄色圆形厚壁孢子。25℃沙氏葡萄糖琼脂培养基培养形成黑绿色绒毛状菌落，镜下见具领状结构的瓶形产孢细胞和花朵样排列的小分生孢子。PAS染色见厚壁孢子。诊断：疣状瓶霉引起的皮肤着色芽生菌病。治疗：给予伊曲康唑胶囊口服及盐酸特比萘芬乳膏外用，同时45～50℃热敷后治愈。

关键词: 着色芽生菌病, 疣状瓶霉

Abstract: A 60- years-old male patient presented with a 16-year history of progressively enlarging erythema and crusting on the right wrist. Physical examination revealed an annular erythema with clear boundary, exudative scab. The lesion was 4 cm×6 cm in size. Many light brown akinetes were seen under microscopy. Olivaceous-black woolly bacterial colonies grew at 25℃ on Sabouraud's dextrose agar medium. Flask-shaped conidiogenous cells with collar structure and ellipsoidal conidia arranged in flower-like shape were seen under microscopically after cultured. PAS staining showed numerous akinetes. The diagnosis of chromoblastomycosis caused by Phialophora verrucosa was made. The patient was treated with oral itraconazole capsules, topical terbinafine hydrochloride cream and 45℃~50℃ hot compress. The lesion healed gradually.

Key words: chromoblastomycosis, Phialophora verrucosa