中国麻风皮肤病杂志 ›› 2016, Vol. 32 ›› Issue (3): 156-158.

• 短篇论著 • 上一篇    下一篇

NB-UVB联合酮康唑洗剂、伊曲康唑治疗中重度马拉色菌毛囊炎疗效评价

周美凤1，陈集敏2，钟建能1，何思华1，赵艳梅2   

  1. 1广东省佛山市顺德区慢性病防治中心皮肤性病科，广东顺德 528300 2广东省佛山市顺德区马洲医院皮肤性病科，广东顺德 528312
  • 出版日期:2016-03-15 发布日期:2018-12-19

Efficacy of NB-UVB combined with ketoconazole lotion and itraconazole in the treatment of moderate to severe Malassezia folliculitis

ZHOU Meifen1 , CHEN Jimin2, ZHONG Jianneng1, HE Sihua1, ZHAO Yanmei2.   

  1. 1.Department of Dermatology, Shunde District Center for Prevention and Management of Chronic Diseases, Foshan 528300, China 2.Department of Dermatology, Mazhou Hospital, Foshan 528312, China
  • Online:2016-03-15 Published:2018-12-19

PDF (PC)

145

摘要： 目的：评价NB-UVB联合酮康唑洗剂、伊曲康唑治疗中重度马拉色菌毛囊炎的疗效。方法：181例中重度马拉色菌毛囊炎患者，随机分为3组。A组58例，给予NB-UVB照射（每周3次）、2%酮康唑洗剂外洗（每天1次）及小剂量伊曲康唑口服（100 mg，日1次），治疗4周；B组60例，给予2%酮康唑洗剂外洗及小剂量伊曲康唑口服；C组63例，仅予小剂量伊曲康唑口服。结果：A，B，C组总有效率分别为 91.38%，78.33%及61.90%，平均治愈时间分别为（27.80±3.15）天、（32.13±3.98）天及（35.83±3.42）天。结论：NB-UVB联合酮康唑洗剂在中重度马拉色菌毛囊炎治疗中能提高伊曲康唑疗效。

关键词: NB-UVB, 马拉色菌毛囊炎

Abstract: Objective: To assess the efficacy of NB-UVB combined with ketoconazole lotion and itraconazole in the treatment of moderate to severe Malassezia folliculitis. Methods: One hundred and eighty one outpatients with moderate to severe Malassezia folliculitis were divided into three groups randomly. Fifty eight patients in group A were treated with NB-UVB, ketoconazole lotion and oral itraconazole. Sixty patients in group B were treated with ketoconazole lotion and oral itraconazole. Sixty three patients in group C were treated with oral itraconazole only. NB-UVB was given 3 times, for 4 weeks, ketoconazole lotion once a day and itraconazole 100mg, once a day for 4 weeks. Results: The total effective rates of group A, B and C was 91.38%, 78.33% and 61.90% and the average cure time was 27.80±3.15/d，32.13±3.98/d and 35.83±3.42/d. Conclusion: NB-UVB combined with ketoconazole lotion and itraconazole is more effective than itraconazole alone in the treatment of moderate to severe Malassezia folliculitis.

Key words: NB-UVB, Malassezia folliculitis, combination therapy