中国麻风皮肤病杂志 ›› 2016, Vol. 32 ›› Issue (4): 248-250.

• 综述 • 上一篇    下一篇

Th17细胞在非节段型白癜风发病机制中的作用

曹 燕1王光平2王林1贾 虹2杨雪源2   

  1. 1.南京中医药大学，南京，210046 2.中国医学科学院皮肤病研究所，南京，210042
  • 出版日期:2016-04-15 发布日期:2018-12-24
  • 通讯作者: 贾虹，E-mail:?jhff2014@163.com; 杨雪源?，E-mail: yangxueyuan@medmail.com.cn

The role of Th17 cells in the pathogenesis of non-segmental vitiligo

CAO Yan1，WANG Guangping2，WANG Lin1, JIA Hong2, YANG Xueyuan2.   

  1. 1.Nanjing University of Chinese Medicine，Nanjing210046，China; 2. Institute of Dermatology，Chinese Academy of Medical Sciences, Nanjing 210042,China
  • Online:2016-04-15 Published:2018-12-24

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摘要： 自身免疫调节异常是非节段型白癜风发病的主要机制,Th17细胞作为新发现的CD4+T辅助性T细胞（Th细胞）亚群，可打破自身免疫耐受，导致自身免疫性黑素细胞破坏，在白癜风发病中起重要作用。本文就Th17细胞在白癜风发病机制中所起作用加以综述。

关键词: 非节段型白癜风, Th17

Abstract: Currently the most recognized mechanism of non-segmental vitiligo is autoimmune dysregulation. Th17 cells as CD4 + T helper T cell (Th cell) subset, can break immune tolerance, lead to autoimmune destruction of melanocytes and play an important role in the pathogenesis of vitiligo. In this paper the role of Th17 cells in the pathogenesis of vitiligo is reviewed.

Key words: non-segmental vitiligo, Th17