中国麻风皮肤病杂志 ›› 2017, Vol. 33 ›› Issue (11): 657-659.

• 论著 • 上一篇    下一篇

超脉冲CO2点阵激光联合外用药治疗顽固性白癜风的疗效评价

刘涛  丁街生  李志武  董秀芹   

  1. 广东省人民医院 广东省医学科学院皮肤科，广东广州，510080

  • 出版日期:2017-11-15 发布日期:2018-12-11
  • 通讯作者: 董秀芹，E-mail: dxq1996@163.com

Effect of ablative fractional CO2 laser combined with topical creams in the treatment of intractable vitiligo

LIU Tao, DING Jiesheng, LI Zhiwu, DONG Xiuqin.   

  1. Department of Dermatology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080 China
  • Online:2017-11-15 Published:2018-12-11
  • Contact: DONG Xiuqin, E-mail: dxq1996@163.com

PDF (PC)

123

摘要： 目的：评价超脉冲CO2点阵激光联合外用药膏治疗顽固性白癜风的临床疗效。方法：将56例顽固性白癜风患者随机分成治疗组29例（皮损52块）和对照组27例（皮损48块），均外用丙酸氟替卡松乳膏及卡泊三醇每日1次，疗程12周。治疗组另给予CO2点阵激光治疗，1次/3周，共4次。12周后评价疗效。结果：治疗组中有效皮损36块，有效率76.6%；对照组有效皮损18块，有效率42.9%，差异有显著性(P<0.01)。结论：点阵激光联合外用药物治疗白癜风比单用药物疗效明显。

关键词: 超脉冲CO2点阵激光, 顽固性白癜风, 联合治疗

Abstract: Objective: To assess the efficacy and safety of CO2 fractional laser combined with topical hormone creams in the treatment of intractable vitiligo. Methods: Fifty six patients with intractable vitiligo were randomly divided into treatment group (29 patients with 47 lesions) and control group (27 patients with 42 lesions). All the patients were treated with topical fluticasone propionate 0.05% cream and calcipotriol ointment, once a day for 12 weeks and the patients in the treatment group were given additional CO2 fractional laser, once three weeks for 4 times. The efficacy in the two groups was assessed. Results: Thirty-six lesions improved in the treatment group, giving an effective rate of 76.6% and 18 lesions improved in the control group, giving an effective rate of 42.9%, with a significant difference between the two groups (P<0.01). Conclusion: CO2 fractional laser combined with topical creams in treatment of intractable vitiligo is more effective than topical creams alone.

Key words: fractional CO2 laser, intractable vitiligo, combination therapy