中国麻风皮肤病杂志 ›› 2024, Vol. 40 ›› Issue (12): 889-892.doi: 10.12144/zgmfskin202412889

• 综述 • 上一篇    下一篇

妊娠类天疱疮研究进展

李霞,张佩莲   

  1. 云南省中医医院，云南中医药大学第一附属医院，云南昆明，650021
  • 出版日期:2024-12-15 发布日期:2024-11-01

Update of pemphigoid gestationis

LI Xia, ZHANG Peilian   

  1. Yunnan Provincial Hospital of Traditional Chinese Medicine, First Affiliated Hospital of Yunnan University of Traditional Chinese Medicine, Kunming 650021,China
  • Online:2024-12-15 Published:2024-11-01

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摘要： 妊娠类天疱疮（PG）是一种罕见的自身免疫性、表皮下大疱性皮肤病，其发病与遗传、环境和免疫等因素有关。临床表现与妊娠多形疹相似。主要治疗药物包括糖皮质激素、免疫抑制剂、免疫球蛋白等。近年来较多文献报道了生物制剂成功治疗PG的案例。本文就PG的发病机制、临床特征及治疗研究进展进行综述。

关键词: 妊娠类天疱疮

Abstract: Pemphigoid gestationis (PG) is a rare autoimmune, subepidermal bullosa skin disease, its pathogenesis is related to genetic, environmental and immune factors. The clinical manifestations are similar to those of pregnancy polymorphous eruption. The main therapeutic drugs are glucocorticoids, immunosuppressants, immunoglobulin and so on. In recent years, many cases of successful treatment of PG with biological agents have been reported. This paper reviews the pathogenesis, clinical features and treatment of PG.

Key words: pemphigoid gestationis