中国麻风皮肤病杂志 ›› 2024, Vol. 40 ›› Issue (7): 480-483.doi: 10.12144/zgmfskin202407480

• 临床研究 • 上一篇    下一篇

衣物消毒剂引起的颗粒状角化不全四例

夏曼琪1，2,邵蕾1，2,周欣1，2,梁毅敏1，2,陈紫妍1，2,黄琼霄3,田歆1，2,刘玉梅1，2
  

  1. 1广州医科大学皮肤病研究所，广东广州，510000；2广州市皮肤病医院皮肤科，广东广州510000；3 广东省泗安医院皮肤科，广东东莞，523001
  • 出版日期:2024-07-15 发布日期:2024-06-11

Four cases of granular parakeratosis induced by disinfectants

XIA Manqi1,2, SHAO Lei1,2, ZHOU Xin1,2, LIANG Yimin1,2, CHEN Ziyan1,2, HUANG Qiongxiao3, TIAN Xin1,2, LIU Yumei1,2   

  1. 1 Institute of Dermatology, Guangzhou Medical University, Guangzhou 510000, China; 2 Guangzhou Dermatology Hospital, Guangzhou 510000, China; 3 Guangdong Sian Hospital, Dongguan 523001, China
  • Online:2024-07-15 Published:2024-06-11

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摘要： 颗粒状角化不全较罕见，临床易误诊。本文报道衣物消毒剂引起的颗粒状角化不全4例，3例患者停止接触消毒剂、全身使用润肤剂后皮损消退，1例患者口服糖皮质激素后皮损明显改善。因此对于皮损表现为对称性红斑伴反复脱屑、呈羊皮纸样外观的患者，皮肤科医生应提高颗粒状角化不全的诊治意识，详细询问消毒剂接触史，指导患者及时停止接触消毒剂并使用润肤剂，必要时可考虑短期系统应用糖皮质激素。

关键词: 颗粒状角化不全, 消毒剂

Abstract: Granular parakeratosis (GP) is rare and easy to be misdiagnosed. We report 4 cases of granular GP caused by clothing disinfectant. The skin lesions of 3 patients subsided after stopping contact with disinfectants and systemic use of emollients, and 1 patient improved significantly after oral glucocorticoids. Dermatologists should strengthen the awareness of diagnosis and treatment of GP with symmetrically erythema with repeated desquamation, take a complete history of exposure to disinfectants, instruct patients to promptly stop using the disinfectants and consider short-term systemic use of glucocorticoids according to the condition.

Key words: granular parakeratosis, disinfectants