中国麻风皮肤病杂志 ›› 2024, Vol. 40 ›› Issue (9): 643-647.doi: 10.12144/zgmfskin202409643

• 临床研究 • 上一篇    下一篇

切取活检法在皮肤非结核分枝杆菌检测中的应用

黄淑琼,周丽君,郭梦露,杨定彬,戚欣雨,朱仁衡,杨学军,彭露,任林,郭桂英   

  1. 乐山市人民医院，四川乐山，614000
  • 出版日期:2024-09-15 发布日期:2024-08-14

Application of incisional biopsy for detection of cutaneous non-tuberculous mycobacterium infection

HUANG Shuqiong, ZHOU Lijun, GUO Menglu, YANG Dingbin, QI Xinyu, ZHU Renheng, YANG Xuejun, PENG Lu, REN Lin, GUO Guiying   

  1. People's Hospital of Leshan, Leshan 614000, China
  • Online:2024-09-15 Published:2024-08-14

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摘要： 目的：明确规范应用切取活检法对提高皮肤NTM病原体检出率的意义。方法：对2021-2024年采用切取活检法进行感染皮肤组织取材临床诊断为非结核分枝杆菌感染的9例患者资料进行回顾性分析，分析内容包括皮肤组织抗酸涂片、组织病理抗酸染色及细菌培养。结果：9例患者中，皮损脓液或皮下组织直接抗酸涂片阳性8例，组织培养6例培养出分枝杆菌，培养阳性率75%，病理抗酸涂片阳性1例。结论：切取活检法可用于皮肤非结核分枝杆菌感染的病原学取材，且取脓液和皮下坏死组织培养阳性检出率更高。

关键词: 非结核分枝杆菌, 切取活检法

Abstract: Objective: To determine the significance of standard application of excision biopsy to improve the detection rate of skin nontuberculous mycobacterium(NTM). Methods: The data of 9 patients who were clinically diagnosed as NTM and performed incisional biopsy during 2021-2024 were analyzed, including acid-fast skin smear, histopathological acid-fast staining and bacterial culture. Results: Among the 9 patients, 8 cases were positive for direct antacid smears in skin abscess or subcutaneous tissue, 6 cases (75%) were positive for tissue culture, and 1 case of pathological antacid smears. Conclusion: Excision biopsy can be used for the etiology of nontuberculous mycobacterium infection of the skin. The positive rate of taking pus and subcutaneous necrotic tissue for culture is higher.

Key words: nontuberculous mycobacterium, incisional biopsy