中国麻风皮肤病杂志 ›› 2025, Vol. 41 ›› Issue (1): 33-36.doi: 10.12144/zgmfskin202501033

• 临床研究 • 上一篇    下一篇

环钻手术、药物注射联合PDL治疗瘢痕疙瘩疗效评价

林萱，毛华荣，庞凯   

  1. 临沂市高新医院皮肤科，山东临沂，276014
  • 出版日期:2025-01-15 发布日期:2024-12-23

Efficacy assessment of trephine resection, combined with medication injection and pulsed dye laser treatment for keloid

LIN Xuan, MAO Huarong, PANG Kai   

  1. Department of Dermatology, Linyi High-Tech Hospital, Linyi 276014, China
  • Online:2025-01-15 Published:2024-12-23

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摘要： 目的：探讨环钻手术、药物注射联合脉冲染料激光（PDL）治疗瘢痕疙瘩的临床疗效。方法：选取 2022 年1月至 2023 年 6月我院皮肤科治疗的瘢痕疙瘩10例，采用环钻手术、药物注射（曲安奈德5 mL、5-氟尿嘧啶0.6 mL、2%利多卡因1 mL）联合脉冲染料激光治疗。结果：所有患者均完成临床治疗与随访，术后随访12个月，术区瘢痕平软，肤色与周边正常皮肤接近，疼痛、瘙痒等症状明显缓解或消失；治愈率80%，有效率90%，90%患者对治疗效果满意。结论：环钻手术配合药物注射加脉冲染料激光进行联合治疗是治疗瘢痕疙瘩安全有效的方法，患者满意度较高。

关键词: 瘢痕疙瘩, 环钻手术, 药物注射, 595脉冲染料激光

Abstract: Objective: To investigate the therapeutic effect of trephine resection, combined with medication injection and pulsed dye laser (PDL) for treating keloid. Methods: Ten keloid patients treated with trephine resection, combined with medication injection(triamcinolone acetonide 5 mL, 5-fluorouracil 0.6 mL, 2% lidocaine 1 mL) and PDL in our hospital from January 2022 to June 2023 were analyzed. Results: The clinical therapy and 12 months follow-up of all patients were completed. The keloid on the operated area were flat and soft, the skin color was close to the normal skin, and the pain and itching were relieved or disappeared. The cure rate and effective rate were 80% and 90%, 90% of the patients were satisfied with the treatment. Conclusions: The combined treatment of trephine resection with drug injection and PDL is a safe and effective treatment for keloid, with higher patient satisfaction.

Key words: keloid, trephine resection, medication injection, 595 pulsed dye laser