中国麻风皮肤病杂志 ›› 2025, Vol. 41 ›› Issue (12): 891-893.doi: 10.12144/zgmfskin202512891

• 病例报告 • 上一篇    下一篇

巨大尖锐湿疣及多部位疣体HPV基因分型检测一例

曾成龙1,陶晓莉2,李海英1,冯婷1,梁媛媛1   

  1. 1空军军医大学西京医院皮肤科，陕西西安，710032； 2锦州医科大学基础医学院病原生物学教研室，辽宁锦州，121000
  • 出版日期:2025-12-15 发布日期:2025-11-28

Giant condyloma acuminatum and HPV genotyping detection of multisite warts: a case report

ZENG Chenglong1, TAO Xiaoli2, LI Haiying1, FENG Ting1, LIANG Yuanyuan1   

  1. 1 Department of Dermatology, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China; 2 Department of Pathogenic Biology, School of Basic Medicine, Jinzhou Medical University, Jinzhou 121000, China
  • Online:2025-12-15 Published:2025-11-28

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摘要： 本文报道一例女性巨大多发尖锐湿疣患者，并对其尿道口、阴道口、外阴、肛周部位皮损进行HPV基因分型检测。检测结果显示，不同部位疣体的HPV基因型别不同，仅外阴部位呈现出单一基因型感染的特征，其它部位表现为多重感染，检出HPV16、35、53和68等高危型。

关键词: 巨大尖锐湿疣, HPV基因型

Abstract: We report a case of a female patient with giant and multiple condylomata acuminata. HPV genotyping was performed on lesions from the urethral orifice, vaginal orifice, vulva, and perianal region. The results revealed distinct HPV genotype distributions across the different sites: only the vulvar lesions were characterized by a single-genotype infection, whereas lesions from all other sites exhibited multiple infections. Notably, high-risk HPV genotypes, including HPV16, 35, 53, and 68, were detected.

Key words: giant condyloma acuminata, HPV genotype