中国麻风皮肤病杂志 ›› 2025, Vol. 41 ›› Issue (9): 679-682.doi: 10.12144/zgmfskin202509679

• 病例报告 • 上一篇    下一篇

瘰疬性皮肤结核一例

罗晓佳,张耀中,姜福琼   

  1. 昆明医科大学第二附属医院皮肤科,云南昆明,650101
  • 出版日期:2025-09-15 发布日期:2025-09-08

Scrofuloderma: a case report

LUO Xiaojia, ZHANG Yaozhong, JIANG Fuqiong   

  1. Department of Dermatology, the Second Affiliated Hospital of Kunming Medical University, Kunming 650101, China
  • Online:2025-09-15 Published:2025-09-08

摘要: 患者,男,74岁,颈前、双侧腋下多发结节、囊肿、坏死、结痂、瘢痕伴疼痛2年。患者曾至当地医院就诊,考虑皮肤感染,予抗炎、止痛、中药等治疗,效果不佳,遂至我院就诊。组织病理检查示:见多核巨细胞;TSPOT阳性;MetaCAP病原微生物核酸高通量测序:检出结核分枝杆菌复合群。诊断:瘰疬性皮肤结核,给予异烟肼、利福平、乙胺丁醇三联口服治疗后皮损明显消退。

关键词: 瘰疬性皮肤结核

Abstract: A 74-year-old male patient presented with multiple nodules, cysts, necrosis, crusting, and scars with pain in the anterior neck and bilateral axillae for 2 years. He was considered a skin infection in a local hospital. He received anti-inflammatory, pain-relieving, and traditional Chinese medicine treatments, but the efficacy was unsatisfactory, so he was referred to our hospital for further diagnosis and treatment. Pathological examination revealed multinucleated giant cells; T-SPOT test was positive; MetaCAP high-throughput sequencing of pathogenic microbial nucleic acids detected Mycobacterium tuberculosis complex. The diagnosis was scrofuloderma. After oral administration of a triple-drug regimen consisting of isoniazid, rifampicin, and ethambutol, the skin lesions subsided significantly.

Key words: scrofuloderma