中国麻风皮肤病杂志 ›› 2021, Vol. 37 ›› Issue (6): 352-355.doi: 10.12144/zgmfskin202106352

• 论著 • 上一篇    下一篇

一例皮肤泛发性球毛壳菌病临床分析

王盛华1,戴文丽2,路麒1,暴芳芳3,李晓莹1   

  1. 1山东第一医科大学附属省立医院临床医学检验部，山东济南，250021；
    2山东第一医科大学附属省立医院皮肤科，山东济南，250021；
    3山东第一医科大学附属皮肤病医院（山东省皮肤病医院，山东省皮肤病性病防治研究所），山东济南，250022
  • 出版日期:2021-06-15 发布日期:2021-05-27
  • 通讯作者: 王盛华，E-mail: wangshenghua79@163.com

Clinical analysis of one case with Chaetomium globosum cutaneous infection

WANG Shenghua1, DAI Wenli2, LU Qi1, BAO Fangfang3, LI Xiaoying1   

  1. 1 Department of Clinical Laboratory, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, China;  
    2 Department of Dermatology, Shandong Provincial Hospital affiliated to Shandong First Medical University, Jinan 250021, China;  
    3 Shandong Provincial Hospital for Skin Diseases & Shandong Provincial Institute of Dermatology and Venereology, Shandong First Medical University, Jinan 250022, China
  • Online:2021-06-15 Published:2021-05-27
  • Contact: WANG Shenghua, E-mail: wangshenghua79@163.com

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摘要： 患者，男，55岁。全身红色结节伴剧痒6个月。皮损真菌荧光染色直接镜检及真菌培养均阳性。提取培养物DNA进行PCR扩增和测序，鉴定为球毛壳菌。给予伊曲康唑、金菌灵及黄芪颗粒口服，联苯苄唑乳膏外用，治疗2个月病情逐渐好转。经文献检索，确认本病例是我国报道的第4例球毛壳菌病。

关键词: 球毛壳菌, 毛壳菌病

Abstract: A 55-year-old man presented with systemic red nodules and intense itching for 6 months. Microscopic examination and fungal culture of the lesions were positive. DNA extracted from the culture was sequenced and identified as Chaetomium globosum. The patient was treated with oral itraconazole, Jinjunling and Huangqi granules and topical bifonazole cream. The patient was improved after two months of treatment. This case is the fourth chaetomycosis caused by Chaetomium globosum reported in China.

Key words: Chaetomium globosum, chaetomycosis