中国麻风皮肤病杂志 ›› 2024, Vol. 40 ›› Issue (5): 350-351.doi: 10.12144/zgmfskin202405350

• 病例报告 • 上一篇    下一篇

托法替布治疗扁平苔藓类天疱疮一例

张帆1,2,陈声利1,2,田洪青1,2   

  1. 1山东第一医科大学附属皮肤病医院，山东济南，250022；2山东省皮肤病性病防治研究所，山东济南，250022
  • 出版日期:2024-05-15 发布日期:2024-04-22

Treatment of lichen planus pemphigoid with Tofacatib: a case report

ZHANG Fan1,2, CHEN Shengli1,2, TIAN Hongqing1,2   

  1. 1 Hospital for Skin Diseases, Shandong First Medical University, Jinan 250022, China; 2 Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences, Jinan 250022, China
  • Online:2024-05-15 Published:2024-04-22

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摘要： 扁平苔藓类天疱疮是一种罕见的获得性自身免疫性皮肤病，临床少见，组织病理学具有特征性，本文报道一例JAK抑制剂托法替布治疗扁平苔藓类天疱疮，治疗一周后患者瘙痒消退，丘疹明显变平，一个月后随访无新发皮损。

关键词: 扁平苔藓类天疱疮 , 诊断, JAK抑制剂

Abstract: Lichenoid planus pemphigoid is a rare acquired autoimmune skin disease, which belongs to a special type of lichen planus, and is characterized by histopathology. We report a case of lichen planus pemphigoid treated with the JAK inhibitor tofacitinib. The patient's pruritus subsided and the papules were significantly flattened after one week of treatment, and there was no new skin lesions during a one-month follow-up.

Key words: lichen planus pemphigoid, diagnosis, JAK inhibitor