中国麻风皮肤病杂志 ›› 2025, Vol. 41 ›› Issue (2): 132-134.doi: 10.12144/zgmfskin202502132

• 病例报告 • 上一篇    下一篇

少根根霉引起皮肤毛霉菌病一例

时晓萱1,2*,于长平1,2*,张铭凯1,2,杨青1,2,陈声利1,2,暴芳芳1,2   

  1. 1山东第一医科大学附属皮肤病医院，山东济南，250022；2山东省皮肤病性病防治研究所，山东济南，250022 *共同第一作者
  • 出版日期:2025-02-15 发布日期:2025-01-22

Mucormycosis caused by Rhizopus arrhizus: a case report

SHI Xiaoxuan1,2*, YU Changping1,2*, ZHANG Mingkai1,2, YANG Qing1,2, CHEN Shengli1,2, BAO Fangfang1,2   

  1. 1 Hospital for Skin Diseases, Shandong First Medical University, Jinan 250022, China; 2 Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences, Jinan 250022, China *Co-first author
  • Online:2025-02-15 Published:2025-01-22

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摘要： 患者，男，81岁。背部皮肤红斑、黑痂伴疼痛1周,病理检查提示真菌感染，真菌培养及PCR测序结果鉴定为少根根霉，诊断为皮肤毛霉菌病。患者有多种基础疾病，发病前曾行背部艾灸治疗。给予系统抗真菌治疗及背部皮损清创术，并积极治疗基础疾病，随访5个月，皮损边缘愈合较好，中央未愈合，可能与中央部位坏死及清创较深有关。

关键词: 少根根霉, 毛霉菌病, 皮肤坏死

Abstract: An 81-year-old male presented with erythema and black scabs on his back, accompanied by pain for a week. Pathological examination demonstrated fungal infection. Fungal culture and PCR sequencing identified Rhizopus arrhizus. The diagnosis of cutaneous mucormycosis was made. The patient suffered from multiple underlying diseases and received moxibustion treatment before the onset of the disease. Systemic antifungal therapy and debridement of back lesions were given, and the underlying diseases were actively treated. After 5-month follow-up, the edges of the skin lesions healed, while the central part did not heal, which might be related to the necrosis and the relatively deep debridement in the central part.

Key words: Rhizopus arrhizus, mucormycosis, necrotic lesion