中国麻风皮肤病杂志 ›› 2019, Vol. 35 ›› Issue (4): 225-228.doi: 10.12144/zgmfskin201904225

• 短篇论著 • 上一篇    下一篇

疣状毛癣菌致母女共患体癣分析

尚盼盼  周亚斌  汪旸  陈伟  万喆  王爱平   

  1. 北京大学第一医院,北京,100034
  • 出版日期:2019-04-15 发布日期:2019-05-20
  • 通讯作者: 王爱平,E-mail:wangap516@163.com

Clinical and laboratory research on the tinea corporis on one mothere and her daughter caused by Trichophyton verrucosum

SHANG Panpan, ZHOU Yabin, WANG Yang, CHEN Wei, WAN Zhe, WANG Aiping   

  1. Peking University First Hospital, Peking 100034,China
  • Online:2019-04-15 Published:2019-05-20
  • Contact: WANG Aiping, E-mail: wangap516@163.com

摘要: 母亲上肢出现皮损1年,女儿面部皮损4个月,皮损表现为大小不一的环形红斑,表面覆有鳞屑及少许痂皮,境界清楚,边缘稍隆起。患者家中养牛。两例皮损真菌镜检均可见菌丝,真菌培养均阳性,分离菌株经表型及分子鉴定,两株菌均为疣状毛癣菌,体外药敏试验显示对伊曲康唑及特比萘芬均敏感。 2例患者经口服和外用抗真菌药物联合治疗获痊愈。

关键词: 疣状毛癣菌, 体癣, 分子鉴定, 药敏试验

Abstract: The lesions located on the mother's up limbs for one year and on daughters face for 4 months. The lesions characterized by annular erythema. The surface was covered with scales and a little scab with boundary clear and slightly uplifted edge. They had a history of raising cattles. The strains isolated from the patients were identified as Trichophyton verrucosum based on the morphological, growth tests and molecular methods. In vitro drug susceptibility test showed Trichophyton verrucosum was sensitive to itraconazole or terbinafin. The patients were cured with oral and topical antifungal drugs.

Key words: Trichophyton verrucosum; tinea corporis, molecular identification, drug sensitivity tests