Abstract: A 46-year-old female presented with infiltrated erythematous plaques on the nasal root for 2 years and prominent swelling of the left eyelid and bilateral preauricular area for 20 days. Skin biopsy on the nose root revealed a dense lymphocytic infiltrate of dermis with perivascular and perifollicular distribution. Immunohistochemical analysis revealed CD2（+），CD3（+），CD7（+），CD20（+），CD30（-），CD56（-），CD4（+），CD8（+），Ki67（10%+），EBER（-）, indicating that the infiltrate was predominantly composed of mature T lymphocytes and a few B lymphocytes. The diagnosis of Jessner's lymphocytic infiltration was made.