Abstract: Objective: To raise the clinical recognition and diagnostic ability of livedoid vasculopathy, and to explore effective treatments. Methods: The clinical and pathological data of patients with livedoid vasculopathy from the year 2010 to 2017 were retrospective analyzed. Results: Totally, there were 23 cases of livedoid vasculopathy including. There were  6 male and 17 female.The average age of onset was 24.86±7.63 years old. The lesions were mainly on the ankle(21/23). The lesions presented with painful purpura, ulceration and ivory atrophy. Biopsy manifested as fibrous degeneration of the small vascular wall and transparent thrombosis within the lumen in the superficial and middle dermis. Anticoagulation, anti-platelet aggregation and fibrinolysis were the main treatments.The disease  was usually successfully treated with pentoxifylline, danazol combinated with aspirin. Conclusion: Livedoid vasculopathy has characteristic clinical and histopathological features, but it is easy to misdiagnose and mistreatment in the early stage. Pentoxifylline may be contributed to the treatment and prevent recurrence of livedoid vasculopathy.

Key words: livedoid vasculopathy, atrophie blanche