Abstract: One 62-year-old male presented with papules and nodules on the back of right hand. The histological features characterized by dermal vascular proliferation, collagen proliferative changes in dermis, lymphohistiocytic infiltrate and bizarre multinucleate cells， positivity of CD68. Combined with the clinical, histopathological changes and immunohistochemical staining, the diagnosis of MCAH was made. We report the third typical case in China, to raise awareness of the disease. The literatures of clinical and histopathological features of this disease were  reviewed.

Key words: multinucleate, angiohistiocytoma