Abstract: We reported a case of plasma cell balanitis and reviewed related literature. A 65-year-old male presented with two erythematous plaques on the glans penis for 2 years. Physical examination showed an asymptomatic shiny red, well-demarcated plaques on the glans penis. Histopathology showed dense infiltrate of plasma cells in the papillary dermis, dilated vessels and minimal hemorrhage. The diagnosis of plasma cell balanitis was made. The patient was treated with 1% pimecrolimus cream, twice daily for 3 months and the lesions got better. The patient is under follow-up.

Key words: plasma cell balanitis, pimecrolimus cream