Abstract: A 58-year-old female presented with scattered erythema and papules on her trunk and limbs with abdominal pain for more than 4 months. Dermatologic examination showed scattered erythema and papules on her trunk and limbs, with porcelain white atrophic patches in the center of the papules which was surrounded by pink edematous border. Biopsy showed the epidermis atrophy and the denatured collagen in the superficial layer of the dermis and the vascular layer was surrounded by lymphocytes and histiocytes. The diagnosis of malignant atrophic papulosis was made. The abdominal pain and the lesions were improved after treated with aspirin, dipyridamole, rabeprazole sodium, mesalazine, azinemide for 1 month. After 2 months the abdominal pain aggravated again and the diagnosis of enterobrosis was made and the patient was treated with laparoscopic surgery with no significant improvement. The patient was died from enterobrosis after 4 months.

Key words: malignant atrophic papulosis, Kohlmeier-Degos syndrome