linear IgA bullous dermatosis,autoimmune bullous disease ,"/> Clinicopathological analysis of 13 cases of linear IgA bullous dermatosis

China Journal of Leprosy and Skin Diseases ›› 2021, Vol. 37 ›› Issue (8): 510-514.doi: 10.12144/zgmfskin202108510

• Clinical Researches • Previous Articles     Next Articles

Clinicopathological analysis of 13 cases of linear IgA bullous dermatosis

QIU Yun, Dilinuer·Abudureyimu, LIANG Junqin, WU Caoying, MAO Lidan, KANG Xiaojing   

  1. People's Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Key Laboratory of Dermatology Research (XJYS1707), Urumqi 830001, China
  • Online:2021-08-15 Published:2021-07-20
  • Contact: KANG Xiaojing, E-mail: drkangxj666@163.com

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Abstract: The data of 13 patients including 11 males and 2 females with linear IgA bullous dermatosis (LABD) in our hospital from July 2012 to June 2019 were analyzed. There were 6 children and 7 adults in the group. The manifestations were blisters and bullae appeared on the erythema or on the normal skin. The blisters were tense with negative Nikosky's sign. Histological examination showed subepidermal blisters in all lesions. Direct immunofluorescence showed linear deposited of IgA in basement membrane. Each of five patient was complicated with rheumatoid arthritis, organic anxiety disorder, paroxysmal nocturnal hemoglobinuria, hypoproteinemia and chronic hepatitis B, respectively. 

Key words: linear IgA bullous dermatosis')">

linear IgA bullous dermatosis, autoimmune bullous disease