Abstract: Seborrheic keratosis (SK) is among the most common benign tumors, which cause and pathogenesis are unclear. A lot of SK-like models were established in order to study the pathogenesis and develop effective drugs, such as genetically engineered mouse models, ultraviolet induced models, xenotrasplantation models and primary cell models. Here we review the update of SK models in recent years.

Key words: keratosis,seborrheic, models