Abstract: A 56-year-old female presented with erythema, nodules, ulcers and pain on both legs for 3 months. Combined with the medical history, clinical manifestations and pathology, the diagnosis of calcified defense was made. The pain symptom of the patient were slightly improved after treatment, while the skin lesions were not significantly improved, and the patient was lost to follow-up 2 months later.

Key words: calciphylaxis, chronic renal failure, secondary hyperparathyroidism