Abstract: A 52-year-old male presented with erythema and blisters on the right head and face with pain for 7 days and fever for 2 days. Physical examination showed edematous erythema can be seen on the right forehead, eye and surrounding skin, with scattered distribution of vesicles and blisters. Combined with the clinical manifestations of decreased vision of the right eye, limited abduction and sensory disturbance of the right face, the patient was diagnosed as herpes zoster, herpetic neuralgia, orbital apex syndrome, keratitis and conjunctivitis. The patient was treated with acyclovir, methylprednisolone, lyrica, ganciclovir ophthalmic gel, eye drops and got improvement.

Key words: herpes zoster ophthalmicus, zoster-associated pain, orbital apex syndrome, keratitis